University Cadi Ayyad-Marrakesh, Morocco
Title: Epidemiology of multi-resistant bacteria in the hospital environment of high-risk infectious units, Ibn Tofail Hospital- Universtary Hospital Center of Marrakech
Adel Elmekes is a PhD student at Cadi Ayyad University - Faculty of Sciences Semlalia, Marrakesh-Morocco. The main goal of his thesis focuses on the study of The clinical and epidemiological risk factors of infections due to multi-drug resistant bacteria in an adult intensive care unit of University Hospital Center (UHC) in Marrakesh-Morocco and the screening of new antimacrobial agents against hospital multidrug resistant bacteria from acinobacteria isolates. He is responsible for hospital hygiene unit and active member of the committee against nosocomial infections.
The objective of this study is to analyze the qualitative and quantitative microbial composition of the environment of high risk infectious units at the Ibn Tofail hospital, CHU Mohammed VI, Marrakech. This is a prospective study carried out at four units (two operating units, two adult intensive care units Intensive Care Unit (ICU) of CHU Mohammed VI Marrakech during a period of four months. The samples concerned inanimate surfaces and the hands of different staff. The level of antibiotic resistance was studied by the diffusion method agar medium. The choice of antibiotics and the criteria for interpretation of the antibiogram were made according to the standards of the European Committee on Antibiograms (EUCAST). More than 95 bacterial strains were isolated from the 125 samples. The antibiotic resistance profile showed that 46% were multidrug resistant strain, 19% of them were Acinetobacter baumannii resistant to imipenem (ABRI), 17 % of the Enterobacteriacae producing extended spectrum of beta-lactamase (ESBLE), and 8 % were methicillin-resistant Stapylococcus aureus (MRSA). The lowest rate (4%) was obtained for Pseudomonas aeruginosa resistant to carbapenem (PARC). The ABRI was mainly found in the inanimate surfaces of ICU, the EBLSE were predominant in the surfaces of the operating units. However, the MRSA was isolated mostly from the staff handprints and the surfaces of the four studied units.The alarming presence of MDR bacteria in the hospital environment urges the hospital actors (biologists, hygienists, clinicians and nursing staff) to double their efforts to control these bacteria.